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vector-borne Trypanosoma brucei parasites develop in artificial human skin and persist as skin tissue forms

Christian Reuter, Fabian Imdahl, Laura Hauf, et al.

A genome-wide knock-out screen for actors of epigenetic silencing reveals new regulators of germline genes and 2-cell like cell state

Nikhil Gupta, Lounis Yakhou, Julien Richard Albert, et al.

Emergent RNA-RNA interactions can promote stability in a nascent phototrophic endosymbiosis

Benjamin H. Jenkins, Finlay Maguire, Guy Leonard, et al.

Remembering immunity: Neuronal ensembles in the insular cortex encode and retrieve specific immune responses

Tamar Koren, Maria Krot, Nadia T. Boshnak, et al.

Discussion

Response to thermal and infection stresses in an American vector of visceral leishmaniasis

Kelsilandia A. Martins, Caroline S. Morais, Susan J. Broughton, et al.

Discussion

The hourglass model of evolutionary conservation during embryogenesis extends to developmental enhancers with signatures of positive selection

Jialin Liu, Rebecca R. Viales, Pierre Khoueiry, et al.

CSPα reduces aggregates and rescues striatal dopamine release in αsynuclein transgenic mice

L Caló, E Hidari, M Wegrzynowicz, et al.

A High Content Screen for Mucin-1-Reducing Compounds Identifies Fostamatinib as a Candidate for Rapid Repurposing for Acute Lung Injury during the COVID-19 pandemic

Maria Alimova, Eriene-Heidi Sidhom, Abhigyan Satyam, et al.

AND

Anti-SARS-CoV-2 IgG from severely ill COVID-19 patients promotes macrophage hyper-inflammatory responses

Willianne Hoepel, Hung-Jen Chen, Sona Allahverdiyeva, et al.

Discussion

Neural plate targeting by in utero nanoinjection (NEPTUNE) reveals a role for Sptbn2 in neurulation and abdominal wall closure

Katrin Mangold, Jan Mašek, Jingyan He, et al.

Discussion

Astrocytes and neurons share brain region-specific transcriptional signatures

Álvaro Herrero-Navarro, Lorenzo Puche-Aroca, Verónica Moreno-Juan, et al.

Discussion

A transient CRISPR/Cas9 expression system for genome editing in Trypanosoma brucei.

Sebastian Shaw, Sebastian Knüsel, Sarah Hoenner, et al.

Automated continuous evolution of proteins in vivo

Ziwei Zhong, Brandon G. Wong, Arjun Ravikumar, et al.